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Icatibant Acetate
CAS No. 138614-30-9
Icatibant Acetate( —— )
Catalog No. M23545 CAS No. 138614-30-9
Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 88 | In Stock |
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| 5MG | 177 | In Stock |
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| 10MG | 282 | In Stock |
|
| 25MG | 475 | In Stock |
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| 50MG | 678 | In Stock |
|
| 100MG | 888 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIcatibant Acetate
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NoteResearch use only, not for human use.
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Brief DescriptionIcatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.
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DescriptionIcatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema.
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In Vitro——
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In VivoAnimal Model:Female mice of the CBA/J (H-2k) strain.Dosage:0.06, 0.3, or 1.5 mg/kg.Administration:Subcutaneous administration twice daily.Result:The length of the large intestine was 93.6±6.8 mm with the 1.5 mg/kg dosage and 94.0±4.1 mm with the 0.3 mg/kg dosage , showing a significant preventive effect on shortening.
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Synonyms——
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PathwayGPCR/G Protein
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TargetBradykinin Receptor
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Recptorbradykinin B2
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Research Area——
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Indication——
Chemical Information
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CAS Number138614-30-9
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Formula Weight1364.57
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Molecular FormulaC61H93N19O15S
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL?(73.28 mM;?Need ultrasonic)
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SMILESCC(=O)O.N[C@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N2C[C@H](O)C[C@H]2C(=O)NCC(=O)N[C@@H](Cc3cccs3)C(=O)N[C@@H](CO)C(=O)N4Cc5ccccc5C[C@@H]4C(=O)N6[C@H]7CCCC[C@H]7C[C@H]6C(=O)N[C@@H](CCCNC(=N)N)C(=O)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Charignon D, et al. Expert Opin Pharmacother. 2012, 13(15):2233-47.
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